Antibodies to Prevent Alzheimer's [Part 2]

Antibodies to Prevent Alzheimer's - On the decline in neurological function of pharmaceutical companies, the Ronald DeMattos researching new therapies to treat and prevent Alzheimer's disease. "What we can show is treatment with a highly specific antibody to attach these patches. We were able to throw a clot or plaque that already exists, "said Ronald DeMattos.

In a healthy brain, beta-amyloid protein should be processed and disposed of the body. However, in people with Alzheimer's disease, the protein accumulates and forms plaques that harden.

The researchers theorize that beta amyloid is a water-soluble coating existing plaques, thus undermining efforts to eliminate the buildup of therapy.

Rather than manipulate genetically drugs to target all beta-amyloid in mice that were bred to be Alzheimer's diseased, DeMattos and his colleagues developed antibodies attached to the plaque and remove the hardened plaque deposits only

"Antibodies were meant to go to the brain and helps your own body to facilitate the removal of materials that accumulate plaque that. By doing so, we hope to alleviate some of the cognitive decline associated with the disease," he said again.

When asked whether the elimination of Alzheimer's plaques lead to improved recall or stop the cognitive decline associated with the disease? "We'll see," said DeMattos.

Patients usually start stockpiling Alzhiemer beta amyloid plaques ten years or more before they are diagnosed, according DeMattos, who said the ultimate goal is to treat people before developing signs of Alzheimer's disease.

Articles novel antibody therapeutics for Alzheimer's disease was published in the journal Neuron.